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Joint Health by NPI is formulated to achieve immediate relief and significant long term repair and improvement. Our Inflammation Factor System is uniquely designed with potent herbal extracts to balance all of the joint inflammation factors, not just COX-2, providing an extraordinary formula for fast acting relief. A dose often gets results in just 30 minutes! Our Alkalinity System addresses systemic metabolic acidosis to reduce the release of inflammatory hydrolytic enzymes by synovial cells in the joints. These are a root trigger of the inflammatory cascade. Balanced minerals include calcium, magnesium, 8 chelated minerals, trace minerals and absorption enhancing co-nutrients, addressing mineral deficiencies and supporting bone health. Our Lubrication & Repair System provides glucosamine, MSM and hyaluronic acid to lubricate and help repair cartilage and other synovial joint tissues. The glucosamine HCl (800 mg which is the equivalent of >1000 mg of the sulfate form) supports the formation and repair of cartilage. MSM (250 mg) increases cellular permeability to reduce inflammation by helping toxins get out, and nutrients get into joints. Hyaluronic acid (10 mg) is a critical joint lubricant. Use of the HCl form of glucosamine avoids a calcium-sulfate interaction (CaSO4 is gypsum). Full Multi-vitamin/Multi-mineral formula. To avoid potential confusion about duplication between the vitamins and minerals in the Joint Health formula and a separate multi-vitamin, potent Multi-vitamin/Multi-mineral content is included in the Joint Health formula. This eliminates, in most cases, the need for separate vitamins and minerals. It includes potent levels of B vitamins to fight stress and balance homocysteine levels, and along with balanced minerals to support bone health.